If you’ve found this page, you’re probably looking for effective methods to treat erectile dysfunction (ED). We’re happy to inform you are at the right place. Let us announce a very efficient and safe therapy able to promote instant erection without any specific effort – this is Trimix.
Erectile dysfunction is defined as the inability to achieve and maintain the erection firm enough for sexual intercourse. A number of men between the ages of 40 and 70 are affected by different types of erectile dysfunction, especially the vasculogenic one.
Most men start taking PDE5 (oral phosphodiesterase type 5 ) inhibitors like Tadalafil (Cialis) or Sildenafil (Viagra) to improve the erection and, yes, oral drugs are quite effective. However, those pills are not suitable for everyone since if a man has some issues with liver or kidneys, heart diseases, or high blood pressure, they would better choose another method of ED treatment.
In case if oral tablets are counter-indicative for you, we recommend choosing Trimix instead. Its name writes itself that the medication is compounded of three ingredients including phentolamine, papaverine, and alprostadil. This is the injectable medication driven into the shaft of the penis with a syringe having a tiny needle.
The drug is obtained in specific compounding pharmacies where qualified pharmacists prepare a mix of the 3 ingredients in required proportions to create a high quality and safe medication. The synergistic effect of Trimix is supposed to be manifested in sustained penile erections which occur immediately right after the injection.
Self-injecting Trimix is a very easy task, so every patient can do it by themselves following the instructions of a doctor.
Before we share a small instruction on how to self-inject Trimix at home, let’s break down each ingredient of the mixture in detail:
Alprostadil is also called Prostaglandin E1 and comes to be a powerful vasodilator that supports the effect by dilating the vessels of erectile tissue (corpus cavernosum).
The main action of this drug is relaxing the muscles of the erectile tissue and expanding the cavernosal arteries thereby causing the rush of blood to the penis.
The half-life of the drug is about 8-10 minutes. The substance is quickly metabolized since more than 80% of it degrades after circulating around the body for once only.
The stenosis of vessels within the penile tissue is caused by alpha-receptors that bind with two hormones released by adrenal glands, and they are epinephrine and norepinephrine.
Phentolamine is an alpha-adrenoceptor antagonist which blocks the alpha-receptors that these hormones are usually bound with to cause vasoconstriction. As a result, the hormones lose their power and this allows the blood to rush into the penis.
The action onset of this medication is ranging between 5-20 minutes and its peak effect appears about 10 minutes after the injection is administered. The half-life of the drug is about 30 minutes but its effects can last up to 2+ hours.
Papaverine is a vasodilator belonging to the class of alkaloids that promote the relaxation of smooth muscles.
The drug works as the inhibitor of the PDE enzyme which breaks the specific molecules in the cell that should help regulate the physiological processes by decreasing the calcium levels within the cell.
When such an enzyme is inhibited by a drug that prevents it from breaking down the required molecules, this results in vasodilation and smooth muscle relaxation in the target tissue, in this case, the penile tissue.
As a result, Trimix injection works as a tool for improving the blood flow into the penis and relaxing the smooth muscles to promote erection. It works within several minutes and allows to receive instant erection firm enough for having sex.
Trimix is considered to be safe for most men. However, it is not recommended to go beyond the daily dose prescribed by the doctor. If you experience a painful erection that lasts for more than 4 hours, urgently call the doctor since such a reaction looks like priapism and requires prompt measures.
Trimix is an injectable medication that is self-injected very easily and the injection should be made just before the sexual intercourse. As the effect of the injection is instant and lasts for about an hour, it would be more comfortable to inject it by yourself and at home.
If the procedure is done with the correct technique, this is a very simple and relatively painless injection. Let’s see the step-by-step technique of Trimix administration:
1. Maintain proper hygiene: wash your hands with water and soap or use an alcohol-based sanitizer.
2. Use the rubber stopper for your injection. Wipe the top of the stopper with an alcohol pad.
3. The syringe with a tiny needle should be inserted into a vial through the rubber stopper. Insert the syringe and draw the required amount of the drug into it (hold to the prescribed dosage).
4. Tap the syringe to make sure there are no air bubbles in it.
5. Locate the injection site on the shaft of the penis. Avoid the midline of the penis and DON’T inject the drug into the visible veins or arteries.
6. The best place to inject Trimix is the sides of the penis. Don’t use the same spot for the injection to avoid scarring.
7. Swipe the injection site with an alcohol wipe.
8. Push the drug to the penile tissue with a syringe and pull the syringe out quickly to prevent bleeding.
9. Apply pressure to the site of injection and then massage the penis to make the drug be distributed across the tissues.
10. Dispose of the syringe when the procedure is completed.
11. The erection is going to occur in 5-15 minutes after the injection.
Please don’t forget to contact a doctor both in case of a prolonged erection or in case if you need some additional consultation before buying the drug or before its administration. Schedule a free consultation here.